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Bobenis
04-10-2005, 03:19 PM
You have people out there complaining and trying to get pot smokers in jail alongside murderers but then this legal killing goes on everyday and no one questions these large evil pharmecutical corporations who do not properly regulate testing on their mulit-billion dollar annual profit drugs? This is just sad that this happens. I suppose many (not all) think well, they are legal so it is ok and turn a blind eye...until it kills their mom, dad, grandma, and/or grandpa. :What the

Drugs killing thousands of seniors yearly

Last Updated Sun, 10 Apr 2005 15:15:13 EDT

CBC News (http://www.cbc.ca/story/canada/national/2005/04/10/seniors-drugs050410.html)

OTTAWA - A CBC News investigation reveals that Canadian seniors account for 44 per cent of adverse drug reactions causing death that are reported to Health Canada, even though they make up just 13 per cent of the population.


CBC's analysis of Canada's adverse drug reaction database, obtained from Health Canada under Access to Information laws, suggests up to 16,500 elderly patients have died due to suspected drug reactions in the last five years.

"The way it's been calculated by CBC I think is quite cautious and is realistic," said Dr. Jim Wright, a clinical pharmacologist who studies the adverse effects of drugs. He's also the managing director of the Therapeutics Initiative at the University of British Columbia.

Older people are more vulnerable to drug reactions partly because they use more drugs than the general population. Seniors are also more vulnerable because they metabolize and excrete drugs more slowly.

But when drugs are being developed, they're rarely tested in seniors, so their effects can be a surprise, says Dr. Robyn Tamblyn, an epidemiologist and researcher at McGill University.

"When a drug is approved to come into the market, you're almost in an experimental situation when you're trying it out on people for which it was never tested," said Tamblyn.

Tamblyn says that in a given year, nearly one in 10 seniors who take drugs will have a reaction serious enough to put them in hospital.

In most cases she says it's a result of inappropriate prescribing: the wrong drug, the wrong dose, the wrong combination of drugs, or even unreadable handwriting on prescriptions that leads to mistakes.

But people are also living longer, in general, according to Dr. Chris MacKnight, one of only 200 Canadian geriatricians, doctors who specialize in treating the elderly.

That means it's more common to live with several chronic conditions, each of which might require its own medication.

MacKnight sees problems created by these multiple prescriptions in the people he treats at the Camp Hill Veterans Memorial Hospital in Halifax.

"The patients we see in the emergency room, probably 75 to 80 per cent of them, have a medication involved in their problem. They've almost always been started on something recently that they've [reacted badly] to," said MacKnight, who's also the president of the Canadian Geriatrics Society.

Drugs to avoid

One tool to help physicians avoid such problems is a study known as the Beers list, which outlines drugs seniors should generally avoid because they are either ineffective in the elderly or put seniors at an unnecessarily high risk when safer alternatives are available.

Last updated in 2003, lead author Donna Fick calls the peer-reviewed list the most user-friendly way for doctors to identify inappropriate drugs for seniors.

Although general practitioners write about 80 per cent of prescriptions, most, including Canadian Medical Association president Albert Schumacher, don't know about or use the Beers list.

Schumacher says he's not alarmed by the number of deaths attributed to Beers list drugs. He says doctors try to balance risk and benefit when they prescribe.

"No it doesn't necessarily raise alarms because, remember, with seniors we're dealing with many life-threatening illnesses," he said.

CBC found that in 2004, 1.5 million Canadian seniors – more than one-third – were given drugs that are either ineffective in the elderly or put seniors at an unnecessarily high risk when safer alternatives are available. This figure was arrived at using data provided by Brogan Inc., a health-care data and research company based in Ottawa.

MacKnight says family doctors are in a tough position when it comes to prescribing for seniors, and they need tools and training to help them do it more safely.

Health researchers like Donna Fick believe a good start would be for doctors to familiarize themselves with the Beers list.

egarrard
04-10-2005, 04:34 PM
There's some validity to this, but I'd suggest that more of the problem lies in the doctors not being able to keep up to date on the lastest information on the thousands of drugs out there. Also, the insurance "providers" have an equal share in the blame.

I've been through this exact thing over the past 4 years.

When I first went to the doctor and was diagnosed with high blood pressure, he put me on some medicine samples that worked just fine. However, when I signed up with the state-run medical program (Tenncare), they balked at providing the medicine. So, we switched to another one that wasn't quite as effective.

A year later, they decided that that medicine was too expensive for Tennesseans, so I got put on 2 differnt other medicines. The same thing happened again with one of them the next year, only by this time I had started having chest pains and shortness of breath.

My doctor ran an EKG and had me rushed to a cardiologist in Nashville within the hour. HE took one look at the EKG, said I was about to have a massive heart attack, but that he wanted a catheterization done first, just to be sure. So, into the cath lab OR I went.

Nothing major was found wrong. HOWEVER, the cath lab cardiologist looked at the medicine, shock his head, and changed a couple of the blood pressure medicines. I stopped having the chest pains, shortness of breath, abnormally high BP, etc. within days.

Not to blame my doctor here, because he can't know as much as the doctors who specialize in any one medical area. He had done the right thing in the beginning. The twits running Tenncare deserve most of the blame for going more on greed than the good of the patients. They wound up paying much more than they originally would have. 2 cardiologists, an OR at one of Nashville's larger hospitals, the nurses, others inviolved, follow-up visits, 2 sleep studies, and a $5000 ventilator.

It's not all on the drug companies. Blame goes all around. Medicine is getting more specialized these days and drug interactions are just one side effect.

wazman
04-10-2005, 05:45 PM
It's more the insurance companies than the doctors, I think. If they decide they won't pay for what the doctor prescribes, you really don't have a choice but to get what they will pay for. And with all the new experimental medicines out there now, you don't know what you're taking.

Bobenis
04-10-2005, 06:02 PM
Yes but the root of it is still the FDA and the ok's they give to these huge companies. The FDA has to worry less about $ and more about scrutinizing over testing to make sure these medications are 100% safe before giving the ok. Why do they do this? Hard to say..maybe govt pressures them into a time frame or funding? Who knows but it is still wrong and needs to be rectified sooner than later.

egarrard
04-10-2005, 06:11 PM
I was quite happy with my daily Bextra. Now they're telling me I just have to live with the pain. Yippee... :negative

Tivon
04-10-2005, 07:34 PM
I was quite happy with my daily Bextra. Now they're telling me I just have to live with the pain. Yippee... :negative

They really need to enter all of these issues into a database.

Do you think UD could do more to find these sorts of problems?:shifty